Consider the daily life of whomever you’re sending a letter to _how many other things might they have on their mind when they read your letter. Maybe they have a meeting in five minutes. Maybe yours is one of 200 letters they have to wade through. Maybe it’s the end of the day and they’re worn out. Giving them a concrete action to take makes it all the more likely that it will “stick” _ they’ll add it to their todo list or their calendar, they’ll pick up the phone, they’ll check out your website, or they’ll respond.
When you know the recipient’s name, sign it “Sincerely yours” or just “Sincerely”, or in the US “Yours truly” is acceptable. Don’t try anything more cutesy or friendly unless a) you know the recipient quite well and are certain you can be informal without seeming disrespectful, or b) you have a “trademark” letter ending that’s part of your public persona (and the talent and popularity to pull it off). Signature and printed name: Signing your name is a minimal assurance that you stand behind what was written.