Return address and date: (Upper right hand corner) Once upon a time, this was necessary in case the letter became separated from the envelope, but I doubt that happens much any more. Even so, this is where your reader is going to look to find your address and the date the letter was written, so it should be there. Mailing address of recipient: (Left_hand side, one line below the return address) This identifies the recipient of the letter. In office environments, letters are often removed from their envelopes and circulated; this helps the letter get back to its rightful recipient.
Remember, you're hoping the person who receives your letter has no memory of your closing at all. The last thing you want is a hiring manager going into an HR meeting with your cover letter in hand, asking the team if they want to meet with "Mr. Kindest Personal Regards."