A Note About Email Business Letters. It might be tempting to leave out the closing when you're communicating by email, but don't give in to that temptation. Although no_closing emails are perfectly fine for everyday communication with your friends and teammates, they'll seem brusque – or worse, unprofessional – to people you don't know as well. You should also use a business letter closing when you're corresponding with someone professionally about an important issue, whether it's a new project or a job opportunity.
When you know the recipient’s name, sign it “Sincerely yours” or just “Sincerely”, or in the US “Yours truly” is acceptable. Don’t try anything more cutesy or friendly unless a) you know the recipient quite well and are certain you can be informal without seeming disrespectful, or b) you have a “trademark” letter ending that’s part of your public persona (and the talent and popularity to pull it off). Signature and printed name: Signing your name is a minimal assurance that you stand behind what was written.