When you're writing a business letter or sending an email message, it's important to close your letter in a professional manner. The ideal ending for a business letter conveys your thanks and respect, without eccentricity or an overly familiar tone. Although it may seem old_fashioned, most business professionals expect written correspondence – whether via a letter or an email – to be written and formatted in a conservative manner.
For instance, in a typical job application, the problem is that the company or organization needs a position filled, and more importantly they need someone who can do the job well and help the organization achieve its mission (which may be more profits, or it may be to save children in Darfur or to end global warming or to cure cancer). You arouse their interest by telling them that you’re the right person for the position and by promising to help them achieve their mission.