If your intent is to persuade the recipient in some way, whether it's to invest money, give you a reference, hire you, partner with you, or fix an issue, create a compelling case for your cause. If, for example, you want the reader to sponsor a charity event, identify any overlap with their company’s philanthropic goals. Convince the reader that helping you would be mutually beneficial, and you will increase your chances of winning their support. Keep your closing paragraph to two sentences. Simply reiterate your reason for writing and thank the reader for considering your request.
However, before using a general salutation (or leaving off a salutation), try to find out the name of the person you are contacting. If you are applying or inquiring about a job and the hiring manager’s name is not included on the job listing, you might look up the title of the employer or hiring manager on the company website. If there is a contact number, you might also call and ask an administrative assistant for the name of the hiring manager. If you are sending a different type of letter, you can still look up the person’s name on the company website, or speak to an administrative assistant or contact at the company for the name of the person you are trying to reach.